Frog Heart

a computer simulation of experiments which may be performed on frog heart

By: David Dewhurst and Malachy Doherty


An interactive, menu-driven and easy to use program which simulates a number of experiments which can be performed on the 'in situ' heart of a pithed frog. High-resolution simulations of contractions of the frog heart, derived from real data, are presented on a scrolling display to simulate a chart recorder. The trace may be paused to facilitate measurement of heart rate or to assess changes in the amplitude of atrial or ventricular contraction. Experiments include:

Interpretation of a typical trace;
the effects of adrenaline;
the effects of acetylcholine (with physostigmine or atropine);
the effects of temperature;
refractory period;
electrical conduction through the heart (Stannius ligatures).

Each experiment is prefaced by introductory text and includes an experiment guide and assignments.

Review of Frog Heart

Language Versions: English

Recommended System Requirements:

  • Windows:
    • Microsoft Windows XP (32 bit), Windows Server 2003 (32-bit), Windows Server 2008 (32 bit), Windows Vista (32 bit), Windows 7 (32 bit and 64 bit), Windows 8
    • 2.33GHz or faster x86-compatible processor, or Intel Atom 1.6GHz or faster processor for netbooks
    • 128MB of RAM (1GB of RAM recommended for netbooks); 128MB of graphics memory
    • Internet Explorer 7.0 or later, Mozilla Firefox 4.0 or later, Google Chrome, Safari 5.0 or later, or Opera 11
  • Mac OS:
    • Mac OS X v10.6, v10.7, or v10.8
    • Intel Core Duo 1.83GHz or faster processor
    • 256MB of RAM; 128MB of graphics memory
    • Safari 5.0 or later, Mozilla Firefox 4.0 or later, Google Chrome, or Opera 11

Target Audience: Undergraduate students of medicine, dentistry and biological sciences.

Price: £250 (multiuser, educational license)

ISBN 1-874758-03-4
©2008 Sheffield Bioscience Programs

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