Frog Heart

a computer simulation of experiments which may be performed on frog heart

By: David Dewhurst and Malachy Doherty


An interactive, menu-driven and easy to use program which simulates a number of experiments which can be performed on the 'in situ' heart of a pithed frog. High-resolution simulations of contractions of the frog heart, derived from real data, are presented on a scrolling display to simulate a chart recorder. The trace may be paused to facilitate measurement of heart rate or to assess changes in the amplitude of atrial or ventricular contraction. Experiments include:

Interpretation of a typical trace;
the effects of adrenaline;
the effects of acetylcholine (with physostigmine or atropine);
the effects of temperature;
refractory period;
electrical conduction through the heart (Stannius ligatures).

Each experiment is prefaced by introductory text and includes an experiment guide and assignments.

Review of Frog Heart

Language Versions: English

Hardware Requirements: Windows: Intel Pentium II 450MHz or faster processor (or equivalent), 128MB of RAM; Microsoft Windows 98, Windows Me, Windows 2000, Windows XP or Windows Server 2003
Macintosh: PowerPC G3 500MHz or faster processor, 128MB of RAM; Mac OS X

Recommended Browser Software: Windows: Internet Explorer; Macintosh: Safari or Firefox; Both: Adobe Flash Player plug-in, version 8 or higher

Target Audience: Undergraduate students of medicine, dentistry and biological sciences.

Price: £250 (multiuser, educational license)

ISBN 1-874758-03-4
©2008 Sheffield Bioscience Programs

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